Silencing repetitive DNA

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منابع مشابه

Silencing repetitive DNA

Some RNAs in mammalian cells can help to silence the DNA they are transcribed from.

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MOM1 mediates DNA-methylation-independent silencing of repetitive sequences in Arabidopsis.

The heterochromatic regions around centromeres of animal and plant chromosomes are composed of tandem repetitive sequences, interspersed with transposons and transposon derivatives. These sequences are largely transcriptionally silent and highly methylated, and are associated with specifically modified histones. Although embedded in heterochromatin, Arabidopsis 5S ribosomal RNA genes are among ...

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Highly Repetitive Satellite DNA

DNA Sequence, Satellite DNA, Cucumis melo The primary sequence of the prominent Cucumis melo satellite DNA is presented. The cloned Hind Ill-repeat unit has a length of 352 bp and a GC-content of 56%. Within this sequence an inverted repeat of 9 bp, including a 286 bp loop, and one direct repeat are shown. Several open reading frames are possible following the sequence in both directions whose ...

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Junk DNA - repetitive sequences

Eukaryote and also human DNA contains large portion of noncoding sequences. As for the coding DNA, the noncoding DNA may be unique or in more identical or similar copies. DNA sequences with high copy numbers are then called repetitive sequences. If the copies of a sequence motif lie adjacent to each other in a block, or an array, we are speaking about tandem repeats, the repetitive sequences di...

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RNAi-mediated DNA silencing

Tucker, and Edwin Chapman (University of Wisconsin, Madison, WI) find that PIP 2 is a plasma membrane dock for synaptotagmin-1 (syt), a transmembrane protein localized in secretory vesicle membranes, when calcium is absent. This dock may ensure speedy and directed fusion in response to calcium influx. The syt dock has two calcium-binding domains in its cytoplasmic region, called C 2 A and C 2 B...

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ژورنال

عنوان ژورنال: eLife

سال: 2017

ISSN: 2050-084X

DOI: 10.7554/elife.29503